Composition

Inclusion Criteria:

• Patient with a pancreatic mass explored by FNA echo-endoscopy

• Patient with a pancreatic mass explored by abdominal CT scan with and without contrast injection and/or biopsy of the mass of secondary lesions via radiological means

• Patient with histologically and/or cytologically proven pancreatic adenocarcinoma

• Patient over 18 years old

• Patient who has given written consent

Exclusion Criteria

• Patient unable to understand or read the consent form

• Subject under guardianship, curatorship, or legal protection

• Patient with a pancreatic tumor whose histological and/or cytological analysis is not adenocarcinoma

• Patient who has started chemotherapy treatment

• Patient with another active cancer diagnosed other than pancreatic cancer

• Pregnant woman

BACAP consists of clinical data at the time of diagnosis and follow-up data (the framework of the observation notebook or CRF (Case Report Form) is only provided upon request).

Data collected at inclusion :

Epidemiological Data

• Month/Year of birth

• Sex

• Profession

• Level of education

• Alcohol consumption

• Tobacco consumption

Clinical Data

• Medical history

• Family history of cancer

• Weight

• Height

• WHO status

• Symptoms at discovery

• Date of first symptoms

Paraclinical Examinations

• Biological data (CBC, liver enzymes, albumin, tumor markers)

• Tumor location

• Diagnostic imaging

Pathology

• Date of diagnostic biopsy and/or surgery

• Pathology of the biopsy and/or surgical specimen

• Tumor stage

• Date of RCP

• Decision of the RCP

Data collected during follow-up

Visits completed at each patient reassessment (CT scan reassessment, change of chemotherapy line, change of treatment), follow-up focuses on routine care according to the habits of each center (no imposed follow-up rhythm)

• Date of visit

• Weight

• WHO status

• Presence of thrombosis

• Biological data (CBC, liver enzymes, albumin, tumor markers)

• Start and end date of chemotherapy line

• Type of chemotherapy

• Number of cycles received

• Grade 3 and 4 toxicities

• Radiotherapy (start/end date, dosage received)

• Surgical data

• Use of growth factors

• Use of anticoagulants

• Use of painkillers

• Date of last news (death, cessation of oncological follow-up, lost to follow-up, withdrawal of consent)

For each patient, the following is available :

• Whole blood: 4 to 6 aliquots of 1ml

• Serum: 4 to 6 aliquots of 500µl

• Plasma: 4 to 6 aliquots of 500µl

• DNA obtained from cytopuncture material

• RNA obtained from cytopuncture material

• Slides from surgical specimens

• Chips from surgical specimens

The biological samples are processed within the biobanks (CRBs) of each center participating in the BACAP project and then stored at the biobank of the CHU of Toulouse.